DianeH

Horse Diagnosed With Lymphoplasmacytic Dermatitis

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I need some help from the experts! My mare has been battling this skin condition on her rear left leg on and off again (mostly on) for nearly a year and a half. I have had a vet look at it several times (more than one vet), she's been on antibotics, been treated with special shampoos, Zymox sprays (we use this daily after cleaning), and many other fungal treatment medications. A few weeks ago we sent scrapings into the state lab for testing and they came back negative for fungal and bacteria, so my vet was out and did a core biopsy last week. Today she called me with the result of Lymphoplasmacytic Dermatitis, but with no cause.

I am at such a loss, my poor mare is seemingly ok, but this needs to go away and without a cause, my vet doesn't know what to perscribe to her.

My next step is the University of Illinois, but that will be a few thousand dollars, which I just don't have to spare right now.

Can anyone please shed any light on this for me? I can post some pics if need be, but this just looks like crusty scabs you would see after turkey mite bites, that's the best description I can think of!

Edited by trails4me

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You might try a cool wet pack of bentonite clay to give her some relief but im not sure if it will help heal the condition. Have you tried any tea tree oil? Its rumored to have healing effects on the skin.

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I've treated lymphoplasmacytic dermatitis in cats rather successfully with prednisolone. Haven't seen it in horses, but would presume its a similar auto-immune cause. Prednisolone would be the first thing I would reach for personally.

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I've treated lymphoplasmacytic dermatitis in cats rather successfully with prednisolone. Haven't seen it in horses, but would presume its a similar auto-immune cause. Prednisolone would be the first thing I would reach for personally.

Thank you, I am going to try an Equine specialist and see what else we can do! I appreciate your help!

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CVM: Would you so kindly give me a definition of this as well? I have googled until my eyes are googled and have not gotten much reading, I'm feeling very hopeless for some cure and a little explanation would sure help!

My vet is great, but she admits that this is a bit out of her scope of expertise and thus the referral to an equine specialist.

Thank you again for your reply, I always appreciate your answers to people on the boards!!

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Not saying this is even close, but first thing that comes to mind is Systemic Lupus:

Systemic lupus erythematosus in a filly.

Geor RJ, Clark EG, Haines DM, Napier PG.

SourceDepartment of Veterinary Internal Medicine, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, Canada.

Abstract

Systemic lupus erythematosus (SLE) was diagnosed in a 2-year-old Standardbred filly. Clinical signs of SLE included weight loss, bilateral symmetric alopecia, seborrhea, oral ulceration, and lymphadenopathy. Abnormal laboratory findings included a Coombs test-positive hemolytic anemia and positive antinuclear antibody test result. Histologic evaluation of multiple skin biopsy specimens revealed interface dermatitis with linear deposition of IgG at the basement membrane zones of the epidermis and hair follicles. The filly did not respond to glucocorticoid treatment and was euthanatized. Necropsy findings included membranous glomerulonephritis and fibrous synovitis. On the basis of these findings, SLE should be considered in the differential diagnosis of immune-mediated skin disease in horses. Definitive diagnosis of SLE relies on recognition of multisystemic disease and confirmatory histopathologic and immunopathologic findings.

PMID:2272881[PubMed - indexed for MEDLINE] Publication Types, MeSH TermsPublication Types

Case Reports

MeSH Terms

Animals

Biopsy/veterinary

Female

Horse Diseases/pathology*

Horses

Liver/pathology

Lupus Erythematosus, Systemic/pathology

Lupus Erythematosus, Systemic/veterinary*

Skin/pathology

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